Technical Information

MagneBind^® 400 Rx

MgCo₃:	400 mg (114 elemental)
CaCo₃:	200 mg (80 elemental)
Folic Acid:	1 mg
Usual Dose	1-2 TID as an adjunct
Est. Phosphate bound per day*	see table below
Typical Serum Mg Range	see table below

MagneBind^® 400 Rx

Tablets p/day	3	4	5	6	7
Magnesium p/day	342 mg	456 mg	570 mg	684 mg	798 mg
Calcium p/day	240 mg	320 mg	400 mg	480 mg	560 mg
Folic acid p/day	3 mg	4 mg	5 mg	6 mg	7 mg
Est. Phosphate bound p/day*	131 mg	175 mg	219 mg	262 mg	306 mg
Typical Serum Mg range	2.2-2.5 mg/dL	2.3-2.8 mg/dL	2.5-3.1 mg/dL	2.6-3.3 mg/dL	2.8-3.5 mg/dL

*Based upon 33.6, 36.75 and 43.8 mg of P bound per tablet respectively for MagneBind^® 200, 300 and 400 Rx. Magnesium carbonate phosphate binding activity calculated from Delmez¹ and Parsons². see calculations

¹Delmez JA, Kelber J, Norwood KY, Giles KS and Slatopolsky E: Magnesium Carbonate as a Phosphate Binder: A Prospective, Controlled, Crossover Study. Kidney Int., Vol. 49, 163-167, 1996. ²Parsons V, Baldwin D, Monitz C, Marsden J, Ball E, Rifkin I: Successful Control of Hyperparathyroidism in Patients on Continuous Ambulatory Peritoneal Dialysis using Magnesium Carbonate and Calcium Carbonate as Phosphate Binders. Nephron 63: 379-383, 1993.